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SMILES: Cc1nnc2C(O)N=C(c3ccccc3F)c3cc(ccc3-n12)C#CCN1C(=O)CCc2ccccc12

InChI Key: InChIKey=SXCZMULKFKAKIS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011636   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011636
PNG
(1-{3-[6-(2-Fluoro-phenyl)-4-hydroxy-1-methyl-4H-2,...)
Show SMILES Cc1nnc2C(O)N=C(c3ccccc3F)c3cc(ccc3-n12)C#CCN1C(=O)CCc2ccccc12 |t:7|
Show InChI InChI=1S/C29H22FN5O2/c1-18-32-33-28-29(37)31-27(21-9-3-4-10-23(21)30)22-17-19(12-14-25(22)35(18)28)7-6-16-34-24-11-5-2-8-20(24)13-15-26(34)36/h2-5,8-12,14,17,29,37H,13,15-16H2,1H3
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n/an/a 50n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair