null
SMILES: COc1cc2CCN(CC#Cc3cc4c(s3)-n3c(C)nnc3CN=C4c3ccccc3Cl)C(=O)c2cc1OC
InChI Key: InChIKey=NMVBVXNQIZWNSD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor receptor (Homo sapiens (Human)) | BDBM50011672 (2-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Research Center Curated by ChEMBL | Assay Description PAF-antagonist activity determined in dog platelets by PAF-binding assay | J Med Chem 34: 1209-21 (1991) BindingDB Entry DOI: 10.7270/Q23X85M1 | |||||||||||
More data for this Ligand-Target Pair |