BDBM50011673 4-(2-Chloro-phenyl)-9-methyl-2-(3-phenoxy-prop-1-ynyl)-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene::CHEMBL20163

SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C#CCOc1ccccc1)c1ccccc1Cl

InChI Key: InChIKey=QQLZIESJNHPHFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50011673 (4-(2-Chloro-phenyl)-9-methyl-2-(3-phenoxy-prop-1-y...) Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCOc1ccccc1)c1ccccc1Cl |c:6| Show InChI InChI=1S/C24H17ClN4OS/c1-16-27-28-22-15-26-23(19-11-5-6-12-21(19)25)20-14-18(31-24(20)29(16)22)10-7-13-30-17-8-3-2-4-9-17/h2-6,8-9,11-12,14H,13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description PAF-antagonist activity determined in dog platelets by PAF-binding assay				J Med Chem 34: 1209-21 (1991) BindingDB Entry DOI: 10.7270/Q23X85M1
					More data for this Ligand-Target Pair