BDBM50011722 CHEMBL3262880

SMILES: Cc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=RDBPWRPWFJWWTN-VAWYXSNFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Mus musculus)	BDBM50011722 (CHEMBL3262880) Show SMILES Cc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C22H24N2O2/c1-18-7-9-19(10-8-18)11-12-21(25)23-13-15-24(16-14-23)22(26)17-20-5-3-2-4-6-20/h2-12H,13-17H2,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at recombinant mouse EBI2 receptor expressed in CHO cells assessed as inhibition of NIBR51-induced intracellular calcium release ...				J Med Chem 57: 3358-68 (2014) Article DOI: 10.1021/jm4019355 BindingDB Entry DOI: 10.7270/Q2BG2QJ5
					More data for this Ligand-Target Pair
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM50011722 (CHEMBL3262880) Show SMILES Cc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C22H24N2O2/c1-18-7-9-19(10-8-18)11-12-21(25)23-13-15-24(16-14-23)22(26)17-20-5-3-2-4-6-20/h2-12H,13-17H2,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at recombinant human EBI2 receptor expressed in CHO cells assessed as inhibition of NIBR51-induced intracellular calcium release ...				J Med Chem 57: 3358-68 (2014) Article DOI: 10.1021/jm4019355 BindingDB Entry DOI: 10.7270/Q2BG2QJ5
					More data for this Ligand-Target Pair