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SMILES: Cc1nnc2CN=C(c3cc(CCc4ccc5CCCc5c4)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=PVLUPPBGGLSUDG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011852   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011852
PNG
(4-(2-Chloro-phenyl)-2-(2-indan-5-yl-ethyl)-9-methy...)
Show SMILES Cc1nnc2CN=C(c3cc(CCc4ccc5CCCc5c4)sc3-n12)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C26H23ClN4S/c1-16-29-30-24-15-28-25(21-7-2-3-8-23(21)27)22-14-20(32-26(22)31(16)24)12-10-17-9-11-18-5-4-6-19(18)13-17/h2-3,7-9,11,13-14H,4-6,10,12,15H2,1H3
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Similars
PubMed
n/an/a 20n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.

J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair