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SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)-c1cc(=O)[nH][nH]1)c1ccccc1Cl

InChI Key: InChIKey=ZVAGYNZXFGWJDJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011859   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011859
PNG
(5-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)-c1cc(=O)[nH][nH]1)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C18H13ClN6OS/c1-9-21-23-15-8-20-17(10-4-2-3-5-12(10)19)11-6-14(27-18(11)25(9)15)13-7-16(26)24-22-13/h2-7H,8H2,1H3,(H2,22,24,26)
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PC cid
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n/an/a 1.00E+3n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.

J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair