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SMILES: CCCCc1ccc(\C=C/c2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1

InChI Key: InChIKey=OKATVFOLMUIIPR-PFONDFGASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011862   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011862
PNG
(2-[2-(4-Butyl-phenyl)-vinyl]-4-(2-chloro-phenyl)-9...)
Show SMILES CCCCc1ccc(\C=C/c2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1 |c:24|
Show InChI InChI=1S/C27H25ClN4S/c1-3-4-7-19-10-12-20(13-11-19)14-15-21-16-23-26(22-8-5-6-9-24(22)28)29-17-25-31-30-18(2)32(25)27(23)33-21/h5-6,8-16H,3-4,7,17H2,1-2H3/b15-14-
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Similars
PubMed
n/an/a 10n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.

J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair