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SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C#CC(=O)N1CCOCC1)c1ccccc1Cl

InChI Key: InChIKey=LZFLVLFYDCMIOZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011865
PNG
(3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CC(=O)N1CCOCC1)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C22H18ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,8-11,13H2,1H3
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n/an/a 260n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Compound tested in vitro for Platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets

J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair