BDBM50011870 3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propenone::CHEMBL285067

SMILES: Cc1nnc2CN=C(c3cc(\C=C\C(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=XXYRUVMJEYVQRW-VOTSOKGWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50011870 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Cc1nnc2CN=C(c3cc(\C=C\C(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl |c:6| Show InChI InChI=1S/C22H20ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-7,12H,8-11,13H2,1H3/b7-6+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.				J Med Chem 34: 1440-6 (1991) BindingDB Entry DOI: 10.7270/Q2BG2MZ9
					More data for this Ligand-Target Pair