BindingDB logo
myBDB logout

BDBM50011875 2-Bromo-4-(2-chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene::BROTIZOLAM::CHEMBL32479

SMILES: Cc1nnc2CN=C(c3cc(Br)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=UMSGKTJDUHERQW-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011875   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(HUMAN)
BDBM50011875
PNG
(2-Bromo-4-(2-chloro-phenyl)-9-methyl-6H-1-thia-5,7...)
Show SMILES Cc1nnc2CN=C(c3cc(Br)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C15H10BrClN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)17)10-6-12(16)22-15(10)21(8)13/h2-6H,7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

PubMed
17.4n/an/an/an/an/an/an/an/a



Rhone-Poulenc Sante

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50011875
PNG
(2-Bromo-4-(2-chloro-phenyl)-9-methyl-6H-1-thia-5,7...)
Show SMILES Cc1nnc2CN=C(c3cc(Br)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C15H10BrClN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)17)10-6-12(16)22-15(10)21(8)13/h2-6H,7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

PubMed
80.5n/an/an/an/an/an/an/an/a



Rhone-Poulenc Sante

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50011875
PNG
(2-Bromo-4-(2-chloro-phenyl)-9-methyl-6H-1-thia-5,7...)
Show SMILES Cc1nnc2CN=C(c3cc(Br)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C15H10BrClN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)17)10-6-12(16)22-15(10)21(8)13/h2-6H,7H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 300n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.


Citation and Details
More data for this
Ligand-Target Pair