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SMILES: [H][C@@]12C[C@H](C[C@@]1(CCO2)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F)NC1CCOCC1OC

InChI Key: InChIKey=MLOPFENXOCOACM-JIUKSFBLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011988   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50011988
PNG
(CHEMBL3263270)
Show SMILES [H][C@@]12C[C@H](C[C@@]1(CCO2)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F)NC1CCOCC1OC |r|
Show InChI InChI=1S/C24H31F3N2O4/c1-31-20-14-32-8-5-19(20)28-18-11-21-23(12-18,6-9-33-21)22(30)29-7-4-15-2-3-17(24(25,26)27)10-16(15)13-29/h2-3,10,18-21,28H,4-9,11-14H2,1H3/t18-,19?,20?,21-,23-/m1/s1
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KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Janssen Research and Development, LLC

Curated by ChEMBL


Assay Description
Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cells

Bioorg Med Chem Lett 24: 2137-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.036
BindingDB Entry DOI: 10.7270/Q2TH8P7P
More data for this
Ligand-Target Pair