BDBM50011995 (Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid::CHEMBL26001::hydroxy(naphthalen-2-yl)methylphosphonic acid

SMILES: OP(O)(O)C(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=UAGWYRYOBTXSBI-UHFFFAOYSA-N

Data: 1 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50011995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athenex Inc. Curated by ChEMBL					Assay Description Non-competitive inhibition of human placental insulin receptor expressed in CHO cell membrane assessed as decrease in insulin-stimulated A2 phosphory...				J Med Chem 61: 4704-4719 (2018) Article DOI: 10.1021/acs.jmedchem.8b00164
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor autophosphorylation in A431 cell membranes				J Med Chem 34: 1577-81 (1991) BindingDB Entry DOI: 10.7270/Q2K0737X
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cells				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Athenex Inc. Curated by ChEMBL					Assay Description Inhibition of human placental insulin receptor expressed in CHO cells assessed as decrease in insulin-stimulated [3H]-2-deoxyglucose uptake preincuba...				J Med Chem 61: 4704-4719 (2018) Article DOI: 10.1021/acs.jmedchem.8b00164
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of insulin receptor autophosphorylation				J Med Chem 34: 1577-81 (1991) BindingDB Entry DOI: 10.7270/Q2K0737X
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50011995 ((Hydroxy-naphthalen-2-yl-methyl)-phosphonic acid |...) Show SMILES OP(O)(O)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C11H11O4P/c12-11(16(13,14)15)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,13-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40E+6	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Curated by ChEMBL					Assay Description The compound was evaluated for its binding affinity towards phosphotyrosine binding pocket of Src protein tryrosine kinase SH2 domain				Bioorg Med Chem Lett 12: 1295-8 (2002) BindingDB Entry DOI: 10.7270/Q2959GW0
					More data for this Ligand-Target Pair