BDBM50012535 CHEMBL3260759

SMILES: COc1ccc(c(C)c1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=MZQCUGJFZQRFIQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50012535 (CHEMBL3260759) Show SMILES COc1ccc(c(C)c1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H25NO6S/c1-18-15-23(32-3)13-14-25(18)20-9-11-22(12-10-20)33-17-21-16-26(34-19(21)2)27(29)28-35(30,31)24-7-5-4-6-8-24/h4-16H,17H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting				Bioorg Med Chem Lett 24: 2212-21 (2014) Article DOI: 10.1016/j.bmcl.2014.02.068 BindingDB Entry DOI: 10.7270/Q2125V6J
					More data for this Ligand-Target Pair