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SMILES: O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1

InChI Key: InChIKey=MNUMPEVJOGZKBX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50012980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012980 (5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C20H24N2O/c23-18-11-13-7-8-15(18)20(22-9-3-4-10-22)19(13)16-12-21-17-6-2-1-5-14(16)17/h1-2,5-6,12-13,15,19-21H,3-4,7-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair