null

SMILES: O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1

InChI Key: InChIKey=SQIRNABIBUHYJX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50012981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50012981 (5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]o...) Show SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1 |TLB:18:7:1.2:5.4,THB:9:8:1.2:5.4,0:1:8.7:5.4| Show InChI InChI=1S/C21H26N2O/c24-19-12-14-8-9-16(19)21(23-10-4-1-5-11-23)20(14)17-13-22-18-7-3-2-6-15(17)18/h2-3,6-7,13-14,16,20-22H,1,4-5,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Polytechnic University Curated by ChEMBL					Assay Description Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortex				J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58
					More data for this Ligand-Target Pair