BDBM50012983 3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1H-indole::CHEMBL339944
SMILES: C1CCN(CC1)C1C2CCC(C=C2)C1c1c[nH]c2ccccc12
InChI Key: InChIKey=RBUWJVDSTORLDM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortex | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortex | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 1a (5-HT1a) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (5HT1A) (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampus | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 1a (5-HT1a) receptor (Mus musculus (Mouse)) | BDBM50012983 (3-(3-Piperidin-1-yl-bicyclo[2.2.2]oct-5-en-2-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Polytechnic University Curated by ChEMBL | Assay Description Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampus | J Med Chem 33: 386-94 (1990) BindingDB Entry DOI: 10.7270/Q23T9G58 | |||||||||||
More data for this Ligand-Target Pair |