BDBM50013046 1-(Thiophen-2-ylmethyl)guanidine::CHEMBL93064::N-Thiophen-2-ylmethyl-guanidine
SMILES: NC(=N)NCc1cccs1
InChI Key: InChIKey=PUKXJLPQHIYTCF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 3 receptor (5HT3) (Mus musculus) | BDBM50013046 (1-(Thiophen-2-ylmethyl)guanidine | CHEMBL93064 | N...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cells | J Med Chem 33: 2721-5 (1990) BindingDB Entry DOI: 10.7270/Q2CJ8F2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (Homo sapiens (Human)) | BDBM50013046 (1-(Thiophen-2-ylmethyl)guanidine | CHEMBL93064 | N...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 3.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati... | Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C | |||||||||||
More data for this Ligand-Target Pair |