BDBM50013414 CHEMBL3263751

SMILES: CCOc1cc(ccc1C(O)=O)C1=NN([C@H](C1)C1CCCC1)c1ccc(C#N)c(C)c1

InChI Key: InChIKey=SYEBWDBFEZMPGA-HSZRJFAPSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50013414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50013414 (CHEMBL3263751) Show SMILES CCOc1cc(ccc1C(O)=O)C1=NN([C@H](C1)C1CCCC1)c1ccc(C#N)c(C)c1 |r,t:13| Show InChI InChI=1S/C25H27N3O3/c1-3-31-24-13-18(9-11-21(24)25(29)30)22-14-23(17-6-4-5-7-17)28(27-22)20-10-8-19(15-26)16(2)12-20/h8-13,17,23H,3-7,14H2,1-2H3,(H,29,30)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor (unknown origin) by Gal4-based cellular assay				J Med Chem 57: 4273-88 (2014) Article DOI: 10.1021/jm500206r BindingDB Entry DOI: 10.7270/Q2D50PGM
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50013414 (CHEMBL3263751) Show SMILES CCOc1cc(ccc1C(O)=O)C1=NN([C@H](C1)C1CCCC1)c1ccc(C#N)c(C)c1 |r,t:13| Show InChI InChI=1S/C25H27N3O3/c1-3-31-24-13-18(9-11-21(24)25(29)30)22-14-23(17-6-4-5-7-17)28(27-22)20-10-8-19(15-26)16(2)12-20/h8-13,17,23H,3-7,14H2,1-2H3,(H,29,30)/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor (unknown origin) by Gal4-based cellular assay				J Med Chem 57: 4273-88 (2014) Article DOI: 10.1021/jm500206r BindingDB Entry DOI: 10.7270/Q2D50PGM
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50013414 (CHEMBL3263751) Show SMILES CCOc1cc(ccc1C(O)=O)C1=NN([C@H](C1)C1CCCC1)c1ccc(C#N)c(C)c1 |r,t:13| Show InChI InChI=1S/C25H27N3O3/c1-3-31-24-13-18(9-11-21(24)25(29)30)22-14-23(17-6-4-5-7-17)28(27-22)20-10-8-19(15-26)16(2)12-20/h8-13,17,23H,3-7,14H2,1-2H3,(H,29,30)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor (unknown origin) by Gal4-based cellular assay				J Med Chem 57: 4273-88 (2014) Article DOI: 10.1021/jm500206r BindingDB Entry DOI: 10.7270/Q2D50PGM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50013414 (CHEMBL3263751) Show SMILES CCOc1cc(ccc1C(O)=O)C1=NN([C@H](C1)C1CCCC1)c1ccc(C#N)c(C)c1 |r,t:13| Show InChI InChI=1S/C25H27N3O3/c1-3-31-24-13-18(9-11-21(24)25(29)30)22-14-23(17-6-4-5-7-17)28(27-22)20-10-8-19(15-26)16(2)12-20/h8-13,17,23H,3-7,14H2,1-2H3,(H,29,30)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor (unknown origin) by Gal4-based cellular assay				J Med Chem 57: 4273-88 (2014) Article DOI: 10.1021/jm500206r BindingDB Entry DOI: 10.7270/Q2D50PGM
					More data for this Ligand-Target Pair