BDBM50013627 22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl)

SMILES: Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1

InChI Key: InChIKey=XZBLPOKMIVGXML-ZCPWPLGKSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50013627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor delta				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappa				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	746	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50013627 (22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...) Show SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 |TLB:17:18:22:7.13.12,3:4:22:7.13.12| Show InChI InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	746	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappa				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
					More data for this Ligand-Target Pair