BDBM50013700 CHEMBL3264535
SMILES: Oc1cc(O)c2C[C@@H](OC(=O)[C@@H]3CC[C@H](F)CC3)[C@H](Oc2c1)c1ccc(O)c(O)c1
InChI Key: InChIKey=HEUZFWKOIMVRPK-USKJCTHSSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heat shock protein HSP 90-beta (Homo sapiens (Human)) | BDBM50013700 (CHEMBL3264535) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Montclair State University Curated by ChEMBL | Assay Description Inhibition of HSP90 (unknown origin) by luciferase refolding assay | Bioorg Med Chem Lett 24: 2263-6 (2014) Article DOI: 10.1016/j.bmcl.2014.03.088 BindingDB Entry DOI: 10.7270/Q2RF5WK6 | |||||||||||
More data for this Ligand-Target Pair |