null

SMILES: OC(=O)CSc1cc(NS(=O)(=O)N2CCN(CC2)c2ccccc2)c2ccccc2c1O

InChI Key: InChIKey=IAZITAFETOAICY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50013869 (CHEMBL3265301) Show SMILES OC(=O)CSc1cc(NS(=O)(=O)N2CCN(CC2)c2ccccc2)c2ccccc2c1O Show InChI InChI=1S/C22H23N3O5S2/c26-21(27)15-31-20-14-19(17-8-4-5-9-18(17)22(20)28)23-32(29,30)25-12-10-24(11-13-25)16-6-2-1-3-7-16/h1-9,14,23,28H,10-13,15H2,(H,26,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Medical School Curated by ChEMBL					Assay Description Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...				J Med Chem 57: 4111-33 (2014) Article DOI: 10.1021/jm500010b BindingDB Entry DOI: 10.7270/Q20003NC
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50013869 (CHEMBL3265301) Show SMILES OC(=O)CSc1cc(NS(=O)(=O)N2CCN(CC2)c2ccccc2)c2ccccc2c1O Show InChI InChI=1S/C22H23N3O5S2/c26-21(27)15-31-20-14-19(17-8-4-5-9-18(17)22(20)28)23-32(29,30)25-12-10-24(11-13-25)16-6-2-1-3-7-16/h1-9,14,23,28H,10-13,15H2,(H,26,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Medical School Curated by ChEMBL					Assay Description Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...				J Med Chem 57: 4111-33 (2014) Article DOI: 10.1021/jm500010b BindingDB Entry DOI: 10.7270/Q20003NC
					More data for this Ligand-Target Pair