BDBM50013912 CHEMBL3260536

SMILES: COCCN(C)C(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=VIMRYZSSMLZOQX-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50013912 (CHEMBL3260536) Show SMILES COCCN(C)C(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C27H27F3N4O2/c1-26(17-19-7-5-4-6-8-19,25(35)33(2)15-16-36-3)23-13-14-31-24-22(18-32-34(23)24)20-9-11-21(12-10-20)27(28,29)30/h4-14,18H,15-17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at GPR119 in mouse GLUTag cells assessed as stimulation of GLP1 secretion by CRE-luciferase reporter gene assay				Bioorg Med Chem Lett 24: 2383-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.023 BindingDB Entry DOI: 10.7270/Q2KP83P1
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50013912 (CHEMBL3260536) Show SMILES COCCN(C)C(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C27H27F3N4O2/c1-26(17-19-7-5-4-6-8-19,25(35)33(2)15-16-36-3)23-13-14-31-24-22(18-32-34(23)24)20-9-11-21(12-10-20)27(28,29)30/h4-14,18H,15-17H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assay				Bioorg Med Chem Lett 24: 2383-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.023 BindingDB Entry DOI: 10.7270/Q2KP83P1
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50013912 (CHEMBL3260536) Show SMILES COCCN(C)C(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C27H27F3N4O2/c1-26(17-19-7-5-4-6-8-19,25(35)33(2)15-16-36-3)23-13-14-31-24-22(18-32-34(23)24)20-9-11-21(12-10-20)27(28,29)30/h4-14,18H,15-17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assay				Bioorg Med Chem Lett 24: 2383-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.023 BindingDB Entry DOI: 10.7270/Q2KP83P1
					More data for this Ligand-Target Pair