BDBM50014066 2-Acetylamino-3-(4-oxiranylmethoxy-phenyl)-propionic acid ethyl ester::CHEMBL42526

SMILES: CCOC(=O)[C@H](Cc1ccc(OCC2CO2)cc1)NC(C)=O

InChI Key: InChIKey=PKFGPHDTEUDHAI-LOACHALJSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50014066 (2-Acetylamino-3-(4-oxiranylmethoxy-phenyl)-propion...) Show SMILES CCOC(=O)[C@H](Cc1ccc(OCC2CO2)cc1)NC(C)=O Show InChI InChI=1S/C16H21NO5/c1-3-20-16(19)15(17-11(2)18)8-12-4-6-13(7-5-12)21-9-14-10-22-14/h4-7,14-15H,3,8-10H2,1-2H3,(H,17,18)/t14?,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University Curated by ChEMBL					Assay Description Inhibitory activity against subtilisin				J Med Chem 33: 1620-34 (1990) BindingDB Entry DOI: 10.7270/Q2HT2N96
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (PCSK9) (Homo sapiens (Human))	BDBM50014066 (2-Acetylamino-3-(4-oxiranylmethoxy-phenyl)-propion...) Show SMILES CCOC(=O)[C@H](Cc1ccc(OCC2CO2)cc1)NC(C)=O Show InChI InChI=1S/C16H21NO5/c1-3-20-16(19)15(17-11(2)18)8-12-4-6-13(7-5-12)21-9-14-10-22-14/h4-7,14-15H,3,8-10H2,1-2H3,(H,17,18)/t14?,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University Curated by ChEMBL					Assay Description Inhibitory activity of the compound was tested against subtilisin				J Med Chem 33: 1620-34 (1990) BindingDB Entry DOI: 10.7270/Q2HT2N96
					More data for this Ligand-Target Pair