BDBM50014210 1-(1H-Indol-3-yl)-2-propanamine::1-(1H-indol-3-yl)propan-2-amine::3-(2-Aminopropyl)indole::CHEMBL30713::DL-3-(2-Aminopropyl)indole::Indopan::alpha-Methyl-1H-indole-3-ethanamine::alpha-Methyl-3-indoleethanamine::alpha-Methyl-beta-indoleethylamine::alpha-methyltryptamine

SMILES: CC(N)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=QSQQQURBVYWZKJ-UHFFFAOYSA-N

Data: 12 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50014210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				J Med Chem 33: 2777-84 (1990) BindingDB Entry DOI: 10.7270/Q2GX49JP
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand				J Med Chem 33: 2777-84 (1990) BindingDB Entry DOI: 10.7270/Q2GX49JP
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysis				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation count...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from human recombinant 5-HT3 receptor expressed in HEK293T cells after 1 to 1.5 hrs by scintillation counting analysis				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Epibatidine from alpha4beta2 nACh receptor in HEK293 cells after 1 to 1.5 hrs by scintillation counting analysis				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Epibatidine from human recombinant alpha4beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor alpha2/beta4 (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor alpha2/beta2 (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCL School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...				Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) Show SMILES CC(N)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assay				Bioorg Med Chem Lett 24: 4754-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK
					More data for this Ligand-Target Pair