BDBM50014224 8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrochloride::CHEMBL555655

SMILES: CSc1ccc(cc1)C1CN2CCCC2c2ccc(Cl)cc12

InChI Key: InChIKey=JSGXTZMCQYACBY-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SLC6A3 (MOUSE)	BDBM50014224 (8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b...) Show SMILES CSc1ccc(cc1)C1CN2CCCC2c2ccc(Cl)cc12 Show InChI InChI=1S/C19H20ClNS/c1-22-15-7-4-13(5-8-15)18-12-21-10-2-3-19(21)16-9-6-14(20)11-17(16)18/h4-9,11,18-19H,2-3,10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for serotonin(5-HT) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Norepinephrine transporter (MOUSE)	BDBM50014224 (8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b...) Show SMILES CSc1ccc(cc1)C1CN2CCCC2c2ccc(Cl)cc12 Show InChI InChI=1S/C19H20ClNS/c1-22-15-7-4-13(5-8-15)18-12-21-10-2-3-19(21)16-9-6-14(20)11-17(16)18/h4-9,11,18-19H,2-3,10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for norepinephrine (NE) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Dopamine transporter (MOUSE)	BDBM50014224 (8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b...) Show SMILES CSc1ccc(cc1)C1CN2CCCC2c2ccc(Cl)cc12 Show InChI InChI=1S/C19H20ClNS/c1-22-15-7-4-13(5-8-15)18-12-21-10-2-3-19(21)16-9-6-14(20)11-17(16)18/h4-9,11,18-19H,2-3,10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for dopamine(DA) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair