BDBM50014241 6-(4-Trifluoromethyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline::CHEMBL94738

SMILES: FC(F)(F)c1ccc(cc1)C1CN2CCCC2c2ccccc12

InChI Key: InChIKey=GFAORPLVFWRVNE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SLC6A3 (MOUSE)	BDBM50014241 (6-(4-Trifluoromethyl-phenyl)-1,2,3,5,6,10b-hexahyd...) Show SMILES FC(F)(F)c1ccc(cc1)C1CN2CCCC2c2ccccc12 Show InChI InChI=1S/C19H18F3N/c20-19(21,22)14-9-7-13(8-10-14)17-12-23-11-3-6-18(23)16-5-2-1-4-15(16)17/h1-2,4-5,7-10,17-18H,3,6,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for serotonin(5-HT) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Norepinephrine transporter (MOUSE)	BDBM50014241 (6-(4-Trifluoromethyl-phenyl)-1,2,3,5,6,10b-hexahyd...) Show SMILES FC(F)(F)c1ccc(cc1)C1CN2CCCC2c2ccccc12 Show InChI InChI=1S/C19H18F3N/c20-19(21,22)14-9-7-13(8-10-14)17-12-23-11-3-6-18(23)16-5-2-1-4-15(16)17/h1-2,4-5,7-10,17-18H,3,6,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for norepinephrine (NE) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Dopamine transporter (MOUSE)	BDBM50014241 (6-(4-Trifluoromethyl-phenyl)-1,2,3,5,6,10b-hexahyd...) Show SMILES FC(F)(F)c1ccc(cc1)C1CN2CCCC2c2ccccc12 Show InChI InChI=1S/C19H18F3N/c20-19(21,22)14-9-7-13(8-10-14)17-12-23-11-3-6-18(23)16-5-2-1-4-15(16)17/h1-2,4-5,7-10,17-18H,3,6,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for dopamine(DA) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair