BDBM50014946 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine::2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine (2-methyl-5-methoxytryptamine)::CHEMBL268800

SMILES: COc1ccc2[nH]c(C)c(CCN)c2c1

InChI Key: InChIKey=TYAPSMFCSAKSOR-UHFFFAOYSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50014946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 6 receptor				J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...				J Med Chem 43: 1011-8 (2000) BindingDB Entry DOI: 10.7270/Q2CF9PBP
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1C receptor was determined in male Sprague-Dawley rat brain.				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1B receptor was determined in male Sprague-Dawley rat brain.				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1D receptor in bovine caudate homogenate				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor was determined in male Sprague-Dawley rat brain.				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor				J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity towards 55-hydroxytryptamine 3 receptor				J Med Chem 43: 1011-8 (2000) BindingDB Entry DOI: 10.7270/Q2CF9PBP
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 2 receptor from male Sprague-Dawley rat brain.				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50014946 (2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | ...) Show SMILES COc1ccc2[nH]c(C)c(CCN)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8-10(5-6-13)11-7-9(15-2)3-4-12(11)14-8/h3-4,7,14H,5-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1E receptor in human cortical homogenate				J Med Chem 33: 755-8 (1990) BindingDB Entry DOI: 10.7270/Q2PG1QPP
					More data for this Ligand-Target Pair