new BindingDB logo
myBDB logout

BDBM50015018 CHEMBL3262404

SMILES: Oc1cccc(NCCN2CCN(CC2)c2ccccc2)c1

InChI Key: InChIKey=CEHQAPDGUFUFDY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015018   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015018
PNG
(CHEMBL3262404)
Show SMILES Oc1cccc(NCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C18H23N3O/c22-18-8-4-5-16(15-18)19-9-10-20-11-13-21(14-12-20)17-6-2-1-3-7-17/h1-8,15,19,22H,9-14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
252n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair