BindingDB PrimarySearch

BDBM50015490 CHEMBL438945::H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2::NPY::NPY, human::NPY, human, rat::Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro- Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His- Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 (NPY)::human Neuropeptide Y

SMILES:

InChI Key: InChIKey=XKWCTHKJQNUFOQ-HRPSIEBRSA-N

Data: 32 KI 9 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50015490
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal Institute of Technology of Zurich Curated by PDSP K_i Database									J Biol Chem 275: 36043-8 (2000) Article DOI: 10.1074/jbc.M000626200 BindingDB Entry DOI: 10.7270/Q2PV6HX1
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assay				Eur J Med Chem 63: 85-94 (2013) Article DOI: 10.1016/j.ejmech.2013.01.044 BindingDB Entry DOI: 10.7270/Q2JH3NKC
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									J Biol Chem 270: 26758-61 (1995) Article DOI: 10.1074/jbc.270.45.26758 BindingDB Entry DOI: 10.7270/Q2Q23XSF
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									J Biol Chem 270: 26762-5 (1995) Article DOI: 10.1074/jbc.270.45.26762 BindingDB Entry DOI: 10.7270/Q2K9362H
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									EMBO J 14: 2806-15 (1995) BindingDB Entry DOI: 10.7270/Q2BK19VW
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y receptor type 1 by radioligand displacement assay				Eur J Med Chem 63: 85-94 (2013) Article DOI: 10.1016/j.ejmech.2013.01.044 BindingDB Entry DOI: 10.7270/Q2JH3NKC
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Broad Institute of MIT and Harvard Curated by ChEMBL					Assay Description Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 mins				Bioorg Med Chem Lett 23: 1834-8 (2013) Article DOI: 10.1016/j.bmcl.2013.01.025 BindingDB Entry DOI: 10.7270/Q2P55PWC
Broad Institute of MIT and Harvard Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal Institute of Technology of Zurich Curated by PDSP K_i Database									J Biol Chem 275: 36043-8 (2000) Article DOI: 10.1074/jbc.M000626200 BindingDB Entry DOI: 10.7270/Q2PV6HX1
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP K_i Database									Mol Pharmacol 60: 534-40 (2001) BindingDB Entry DOI: 10.7270/Q2BC3X35
					More data for this Ligand-Target Pair
NPY2R (RAT)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U410 Curated by PDSP K_i Database									Mol Pharmacol 60: 124-34 (2001) Article DOI: 10.1124/mol.60.1.124 BindingDB Entry DOI: 10.7270/Q2C827VN
U410 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPY5R (Rat 6B)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Corporation Curated by PDSP K_i Database									J Biol Chem 271: 26315-9 (1996) Article DOI: 10.1074/jbc.271.42.26315 BindingDB Entry DOI: 10.7270/Q20G3HPR
Bayer Corporation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPY5R (Rat 6B)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Corporation Curated by PDSP K_i Database									J Biol Chem 271: 26315-9 (1996) Article DOI: 10.1074/jbc.271.42.26315 BindingDB Entry DOI: 10.7270/Q20G3HPR
Bayer Corporation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of Cy5-pNPY from human Y1 receptor expressed in HEL cells after 90 to 120 mins by flow cytometry				J Med Chem 56: 8422-31 (2013) Article DOI: 10.1021/jm4008505 BindingDB Entry DOI: 10.7270/Q25X2BC9
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									J Biol Chem 270: 26758-61 (1995) Article DOI: 10.1074/jbc.270.45.26758 BindingDB Entry DOI: 10.7270/Q2Q23XSF
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									EMBO J 14: 2806-15 (1995) BindingDB Entry DOI: 10.7270/Q2BK19VW
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal Institute of Technology of Zurich Curated by PDSP K_i Database									J Biol Chem 275: 36043-8 (2000) Article DOI: 10.1074/jbc.M000626200 BindingDB Entry DOI: 10.7270/Q2PV6HX1
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Corporation Curated by PDSP K_i Database									J Biol Chem 271: 26315-9 (1996) Article DOI: 10.1074/jbc.271.42.26315 BindingDB Entry DOI: 10.7270/Q20G3HPR
Bayer Corporation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPY2R (RAT)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
U410 Curated by PDSP K_i Database									Mol Pharmacol 60: 124-34 (2001) Article DOI: 10.1124/mol.60.1.124 BindingDB Entry DOI: 10.7270/Q2C827VN
U410 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of Cy5-pNPY from human Y2 receptor expressed in CHO cells after 90 to 120 mins by flow cytometry				J Med Chem 56: 8422-31 (2013) Article DOI: 10.1021/jm4008505 BindingDB Entry DOI: 10.7270/Q25X2BC9
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP K_i Database									Mol Pharmacol 60: 534-40 (2001) BindingDB Entry DOI: 10.7270/Q2BC3X35
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP K_i Database									Mol Pharmacol 60: 534-40 (2001) BindingDB Entry DOI: 10.7270/Q2BC3X35
					More data for this Ligand-Target Pair
NPY2R (MOUSE)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by PDSP K_i Database									J Biol Chem 271: 16435-8 (1996) Article DOI: 10.1074/jbc.271.28.16435 BindingDB Entry DOI: 10.7270/Q2XK8D36
Merck Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
PPYR1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									J Biol Chem 270: 26762-5 (1995) Article DOI: 10.1074/jbc.270.45.26762 BindingDB Entry DOI: 10.7270/Q2K9362H
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of Cy5-pNPY from human Y5 receptor expressed in human HEC-1B cells after 90 to 120 mins by flow cytometry				J Med Chem 56: 8422-31 (2013) Article DOI: 10.1021/jm4008505 BindingDB Entry DOI: 10.7270/Q25X2BC9
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Curated by PDSP K_i Database									J Biol Chem 270: 22661-4 (1995) Article DOI: 10.1074/jbc.270.39.22661 BindingDB Entry DOI: 10.7270/Q2TT4PGD
Bristol Myers Squibb Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Curated by PDSP K_i Database									J Biol Chem 270: 22661-4 (1995) Article DOI: 10.1074/jbc.270.39.22661 BindingDB Entry DOI: 10.7270/Q2TT4PGD
Bristol Myers Squibb Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5) (Mus musculus (Mouse))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by PDSP K_i Database									J Biol Chem 271: 16435-8 (1996) Article DOI: 10.1074/jbc.271.28.16435 BindingDB Entry DOI: 10.7270/Q2XK8D36
Merck Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
PPYR1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal Institute of Technology of Zurich Curated by PDSP K_i Database									J Biol Chem 275: 36043-8 (2000) Article DOI: 10.1074/jbc.M000626200 BindingDB Entry DOI: 10.7270/Q2PV6HX1
					More data for this Ligand-Target Pair
PPYR1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of Cy5-[K4]hPP from human Y4 receptor expressed in CHO cells after 90 to 120 mins by flow cytometry				J Med Chem 56: 8422-31 (2013) Article DOI: 10.1021/jm4008505 BindingDB Entry DOI: 10.7270/Q25X2BC9
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
NPFF (RAT)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Juvantia Pharma, Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 825-32 (2003) Article DOI: 10.1124/jpet.102.047118 BindingDB Entry DOI: 10.7270/Q2WS8RS2
Juvantia Pharma, Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y (RAT)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 93: 4661-5 (1996) Article DOI: 10.1073/pnas.93.10.4661 BindingDB Entry DOI: 10.7270/Q22B8WJN
Amgen Curated by PDSP K_i Database					More data for this Ligand-Target Pair
NPFF2 (RAT)	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Juvantia Pharma, Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 305: 825-32 (2003) Article DOI: 10.1124/jpet.102.047118 BindingDB Entry DOI: 10.7270/Q2WS8RS2
Juvantia Pharma, Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
The University of Mississippi Curated by ChEMBL					Assay Description Inhibition of neuropeptide Y1 receptor in human SK-N-MC cells after 60 mins by scintillation counting				J Nat Prod 72: 2172-6 (2009) Article DOI: 10.1021/np900287e BindingDB Entry DOI: 10.7270/Q2MC910T
The University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assay				Eur J Med Chem 63: 85-94 (2013) Article DOI: 10.1016/j.ejmech.2013.01.044 BindingDB Entry DOI: 10.7270/Q2JH3NKC
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y receptor type 1 by radioligand displacement assay				Eur J Med Chem 63: 85-94 (2013) Article DOI: 10.1016/j.ejmech.2013.01.044 BindingDB Entry DOI: 10.7270/Q2JH3NKC
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Broad Institute of MIT and Harvard Curated by ChEMBL					Assay Description Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 mins				Bioorg Med Chem Lett 23: 1834-8 (2013) Article DOI: 10.1016/j.bmcl.2013.01.025 BindingDB Entry DOI: 10.7270/Q2P55PWC
Broad Institute of MIT and Harvard Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Displacement of [125I]-NPY from Y1 receptor in human MCF7 cells in presence of 1 uM BBN				Bioorg Med Chem Lett 23: 687-92 (2013) Article DOI: 10.1016/j.bmcl.2012.11.110 BindingDB Entry DOI: 10.7270/Q2G16246
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.				J Med Chem 43: 346-50 (2000) BindingDB Entry DOI: 10.7270/Q2XK8DS5
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y2 receptor by radioligand displacement assay				Bioorg Med Chem 21: 2764-71 (2013) Article DOI: 10.1016/j.bmc.2013.03.016 BindingDB Entry DOI: 10.7270/Q2N87C5Q
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair
PPYR1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human Y4 receptor expressed in sf9 cells assessed as hydrolysis of [gamma-33P]GTP after 2 mins by scintillation counting analysis				J Med Chem 56: 8422-31 (2013) Article DOI: 10.1021/jm4008505 BindingDB Entry DOI: 10.7270/Q25X2BC9
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against Y2 receptor of rabbit kidney membrane				Bioorg Med Chem Lett 3: 937-942 (1993) Article DOI: 10.1016/S0960-894X(00)80696-4 BindingDB Entry DOI: 10.7270/Q2H9954N
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50015490 (CHEMBL438945 \| H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Synthesis Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y1 receptor by radioligand displacement assay				Bioorg Med Chem 21: 2764-71 (2013) Article DOI: 10.1016/j.bmc.2013.03.016 BindingDB Entry DOI: 10.7270/Q2N87C5Q
Institute of Organic Synthesis Curated by ChEMBL					More data for this Ligand-Target Pair