BDBM50015509 5-(2-Amino-4-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL301814

SMILES: Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(Cl)cc1N

InChI Key: InChIKey=WCYQERUNPFJALR-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50015509 (5-(2-Amino-4-chloro-phenyl)-1,3-dimethyl-1,6-dihyd...) Show SMILES Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(Cl)cc1N Show InChI InChI=1S/C13H12ClN5O/c1-6-10-11(19(2)18-6)13(20)17-12(16-10)8-4-3-7(14)5-9(8)15/h3-5H,15H2,1-2H3,(H,16,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Genova Curated by ChEMBL					Assay Description Binding affinity at bovine Adenosine A1 receptor.				J Med Chem 45: 4875-87 (2002) BindingDB Entry DOI: 10.7270/Q2N87BHS
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50015509 (5-(2-Amino-4-chloro-phenyl)-1,3-dimethyl-1,6-dihyd...) Show SMILES Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(Cl)cc1N Show InChI InChI=1S/C13H12ClN5O/c1-6-10-11(19(2)18-6)13(20)17-12(16-10)8-4-3-7(14)5-9(8)15/h3-5H,15H2,1-2H3,(H,16,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Center for Bio-Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]-CHA binding to Adenosine A1 receptor in rat brain membranes				J Med Chem 33: 1708-13 (1990) BindingDB Entry DOI: 10.7270/Q2CZ3643
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50015509 (5-(2-Amino-4-chloro-phenyl)-1,3-dimethyl-1,6-dihyd...) Show SMILES Cc1nn(C)c2c1nc([nH]c2=O)-c1ccc(Cl)cc1N Show InChI InChI=1S/C13H12ClN5O/c1-6-10-11(19(2)18-6)13(20)17-12(16-10)8-4-3-7(14)5-9(8)15/h3-5H,15H2,1-2H3,(H,16,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in rat brain membrane preparations using N6-[3H]-cyclohexyladenosine as a radioligand				J Med Chem 30: 91-6 (1987) BindingDB Entry DOI: 10.7270/Q2Q23Z84
					More data for this Ligand-Target Pair