BDBM50015585 CHEMBL3259823

SMILES: CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccc(C)cc1)c1ccc(cc1)S(=O)(=O)NC(=S)NCc1ccccc1

InChI Key: InChIKey=WTDCITYAOVFRGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50015585 (CHEMBL3259823) Show SMILES CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccc(C)cc1)c1ccc(cc1)S(=O)(=O)NC(=S)NCc1ccccc1 |t:10| Show InChI InChI=1S/C32H33N5O2S2/c1-23-9-11-26(12-10-23)31-21-30(25-13-15-27(16-14-25)36(2)3)34-37(31)28-17-19-29(20-18-28)41(38,39)35-32(40)33-22-24-7-5-4-6-8-24/h4-20,31H,21-22H2,1-3H3,(H2,33,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of aldose reductase in rat lens by spectrophotometer analysis				Eur J Med Chem 80: 209-17 (2014) Article DOI: 10.1016/j.ejmech.2014.04.046 BindingDB Entry DOI: 10.7270/Q2PC33ZJ
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