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BDBM50015586 CHEMBL3260155

SMILES: CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccccc1Cl)c1ccc(cc1)S(=O)(=O)NC(=S)NCc1ccccc1

InChI Key: InChIKey=QQYYCLHUDLWINO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015586   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50015586
PNG
(CHEMBL3260155)
Show SMILES CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccccc1Cl)c1ccc(cc1)S(=O)(=O)NC(=S)NCc1ccccc1 |t:10|
Show InChI InChI=1S/C31H30ClN5O2S2/c1-36(2)24-14-12-23(13-15-24)29-20-30(27-10-6-7-11-28(27)32)37(34-29)25-16-18-26(19-17-25)41(38,39)35-31(40)33-21-22-8-4-3-5-9-22/h3-19,30H,20-21H2,1-2H3,(H2,33,35,40)
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MMDB

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Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Jamia Hamdard (Hamdard University)

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase in rat lens by spectrophotometer analysis


Eur J Med Chem 80: 209-17 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.046
BindingDB Entry DOI: 10.7270/Q2PC33ZJ
More data for this
Ligand-Target Pair