BDBM50015588 CHEMBL3260158

SMILES: CCCCNC(=S)NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(cc1)N(C)C

InChI Key: InChIKey=JOXMSJXZLXVZJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50015588 (CHEMBL3260158) Show SMILES CCCCNC(=S)NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(cc1)N(C)C |c:19| Show InChI InChI=1S/C28H32ClN5O2S2/c1-4-5-18-30-28(37)32-38(35,36)25-16-14-24(15-17-25)34-27(21-6-10-22(29)11-7-21)19-26(31-34)20-8-12-23(13-9-20)33(2)3/h6-17,27H,4-5,18-19H2,1-3H3,(H2,30,32,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of aldose reductase in rat lens by spectrophotometer analysis				Eur J Med Chem 80: 209-17 (2014) Article DOI: 10.1016/j.ejmech.2014.04.046 BindingDB Entry DOI: 10.7270/Q2PC33ZJ
					More data for this Ligand-Target Pair