BDBM50015589 CHEMBL3260160

SMILES: CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccccc1)c1ccc(cc1)S(=O)(=O)NC(=S)NC1CCCCC1

InChI Key: InChIKey=TWOPZJKXVFEKDX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50015589 (CHEMBL3260160) Show SMILES CN(C)c1ccc(cc1)C1=NN(C(C1)c1ccccc1)c1ccc(cc1)S(=O)(=O)NC(=S)NC1CCCCC1 |t:10| Show InChI InChI=1S/C30H35N5O2S2/c1-34(2)25-15-13-22(14-16-25)28-21-29(23-9-5-3-6-10-23)35(32-28)26-17-19-27(20-18-26)39(36,37)33-30(38)31-24-11-7-4-8-12-24/h3,5-6,9-10,13-20,24,29H,4,7-8,11-12,21H2,1-2H3,(H2,31,33,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of aldose reductase in rat lens by spectrophotometer analysis				Eur J Med Chem 80: 209-17 (2014) Article DOI: 10.1016/j.ejmech.2014.04.046 BindingDB Entry DOI: 10.7270/Q2PC33ZJ
					More data for this Ligand-Target Pair