BDBM50015757 4-Piperazin-1-yl-[1,2,4]triazolo[4,3-a]quinoxaline::CHEMBL73152

SMILES: C1CN(CCN1)c1nc2ccccc2n2cnnc12

InChI Key: InChIKey=NVIFIHUCMXMNBE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 1 (Rattus norvegicus)	BDBM50015757 (4-Piperazin-1-yl-[1,2,4]triazolo[4,3-a]quinoxaline...) Show SMILES C1CN(CCN1)c1nc2ccccc2n2cnnc12 Show InChI InChI=1S/C13H14N6/c1-2-4-11-10(3-1)16-12(13-17-15-9-19(11)13)18-7-5-14-6-8-18/h1-4,9,14H,5-8H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity for Adenosine A1 receptor in corpora striata of rats using [3H]NECA				J Med Chem 33: 2240-54 (1990) BindingDB Entry DOI: 10.7270/Q2PR7WKF
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50015757 (4-Piperazin-1-yl-[1,2,4]triazolo[4,3-a]quinoxaline...) Show SMILES C1CN(CCN1)c1nc2ccccc2n2cnnc12 Show InChI InChI=1S/C13H14N6/c1-2-4-11-10(3-1)16-12(13-17-15-9-19(11)13)18-7-5-14-6-8-18/h1-4,9,14H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.				J Med Chem 33: 2240-54 (1990) BindingDB Entry DOI: 10.7270/Q2PR7WKF
					More data for this Ligand-Target Pair