null

SMILES: CCOC(=O)c1sc(nc1-c1cccc(Cl)c1Cl)-c1ccncc1

InChI Key: InChIKey=DLGUSEYAXCNOQL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50016129 (CHEMBL3261240) Show SMILES CCOC(=O)c1sc(nc1-c1cccc(Cl)c1Cl)-c1ccncc1 Show InChI InChI=1S/C17H12Cl2N2O2S/c1-2-23-17(22)15-14(11-4-3-5-12(18)13(11)19)21-16(24-15)10-6-8-20-9-7-10/h3-9H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assay				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM50016129 (CHEMBL3261240) Show SMILES CCOC(=O)c1sc(nc1-c1cccc(Cl)c1Cl)-c1ccncc1 Show InChI InChI=1S/C17H12Cl2N2O2S/c1-2-23-17(22)15-14(11-4-3-5-12(18)13(11)19)21-16(24-15)10-6-8-20-9-7-10/h3-9H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	451	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assay				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair