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SMILES: c1ccc(cc1)-c1nc(sc1-c1nn[nH]n1)-c1ccncc1

InChI Key: InChIKey=KVFBXYUQVDJRON-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50016144 (CHEMBL3261496) Show SMILES c1ccc(cc1)-c1nc(sc1-c1nn[nH]n1)-c1ccncc1 Show InChI InChI=1S/C15H10N6S/c1-2-4-10(5-3-1)12-13(14-18-20-21-19-14)22-15(17-12)11-6-8-16-9-7-11/h1-9H,(H,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assay				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM50016144 (CHEMBL3261496) Show SMILES c1ccc(cc1)-c1nc(sc1-c1nn[nH]n1)-c1ccncc1 Show InChI InChI=1S/C15H10N6S/c1-2-4-10(5-3-1)12-13(14-18-20-21-19-14)22-15(17-12)11-6-8-16-9-7-11/h1-9H,(H,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	452	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assay				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair