BDBM50016468 CHEMBL3265096

SMILES: CCCOc1ccc(\C=C2\C(=O)Nc3ccccc23)c(OCCC)c1

InChI Key: InChIKey=CODRRTHDNKXPKO-QGOAFFKASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50016468 (CHEMBL3265096) Show SMILES CCCOc1ccc(\C=C2\C(=O)Nc3ccccc23)c(OCCC)c1 Show InChI InChI=1S/C21H23NO3/c1-3-11-24-16-10-9-15(20(14-16)25-12-4-2)13-18-17-7-5-6-8-19(17)22-21(18)23/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,22,23)/b18-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Science and Peking Union Medical College Curated by ChEMBL					Assay Description Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assay				Eur J Med Chem 81: 277-88 (2014) Article DOI: 10.1016/j.ejmech.2014.05.027 BindingDB Entry DOI: 10.7270/Q2736SGW
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50016468 (CHEMBL3265096) Show SMILES CCCOc1ccc(\C=C2\C(=O)Nc3ccccc23)c(OCCC)c1 Show InChI InChI=1S/C21H23NO3/c1-3-11-24-16-10-9-15(20(14-16)25-12-4-2)13-18-17-7-5-6-8-19(17)22-21(18)23/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,22,23)/b18-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Science and Peking Union Medical College Curated by ChEMBL					Assay Description Binding affinity to MDM2 in human MCF7 cells assessed as inhibition of MDM2-p53 interaction				Eur J Med Chem 81: 277-88 (2014) Article DOI: 10.1016/j.ejmech.2014.05.027 BindingDB Entry DOI: 10.7270/Q2736SGW
					More data for this Ligand-Target Pair