BDBM50016534 1-(4-azido-5-{[(1,2,3,3-tetrahydroxy-1,2,3-trioxidotriphosphanyl)oxy]methyl}tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione::CHEMBL311075

SMILES: Cc1cn(C2CC(N=[N+]=[N-])C(COP(O)(=O)P(O)(=O)P(O)(O)=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=MMUDSKLTJHHBFM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50016534 (1-(4-azido-5-{[(1,2,3,3-tetrahydroxy-1,2,3-trioxid...) Show SMILES Cc1cn(C2CC(N=[N+]=[N-])C(COP(O)(=O)P(O)(=O)P(O)(O)=O)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C10H16N5O11P3/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(26-8)4-25-28(21,22)29(23,24)27(18,19)20/h3,6-8H,2,4H2,1H3,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rA)-oligo(dT) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
					More data for this Ligand-Target Pair