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BDBM50016564 CHEMBL3272448

SMILES: CN(C)[C@@H]1CC[C@@H](N(Cc2ccccc2)C1)c1ccccc1

InChI Key: InChIKey=JKKRCPMOCSTNPD-WOJBJXKFSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016564   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine N-methyltransferase


(Cavia porcellus)		BDBM50016564
PNG
(CHEMBL3272448)
Show SMILES CN(C)[C@@H]1CC[C@@H](N(Cc2ccccc2)C1)c1ccccc1 |r|
Show InChI InChI=1S/C20H26N2/c1-21(2)19-13-14-20(18-11-7-4-8-12-18)22(16-19)15-17-9-5-3-6-10-17/h3-12,19-20H,13-16H2,1-2H3/t19-,20-/m1/s1
UniProtKB/SwissProt

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PC sid
UniChem

Similars
PubMed
 3.16E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of histamine N-methyltransferase in guinea pig brain using S-adenosyl-L-methionine-14C as substrate by scintillation spectrophotometer

J Med Chem 19: 117-22 (1976)


BindingDB Entry DOI: 10.7270/Q29W0H2G
More data for this
Ligand-Target Pair