BDBM50016629 4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(3-phenyl-propyl)-benzenesulfonamide::CHEMBL19711

SMILES: Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCCCc1ccccc1

InChI Key: InChIKey=GBBYUIDRYGAQCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016629 (4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(3-phen...) Show SMILES Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCCCc1ccccc1 Show InChI InChI=1S/C18H18ClN3O4S/c19-13-8-9-15(14(11-13)16-17(23)22-18(24)21-16)27(25,26)20-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,20,23H,4,7,10H2,(H2,21,22,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair