BDBM50016632 4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(4-fluoro-phenyl)-benzenesulfonamide::CHEMBL274727

SMILES: Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=XLZXKIOMTGCMLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016632 (4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(4-fluo...) Show SMILES Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C15H11ClFN3O4S/c16-8-1-6-12(11(7-8)13-14(21)19-15(22)18-13)25(23,24)20-10-4-2-9(17)3-5-10/h1-7,20-21H,(H2,18,19,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair