BDBM50016645 5-[5-Chloro-2-(4-chloro-phenylmethanesulfonyl)-phenyl]-imidazolidine-2,4-dione::CHEMBL19649

SMILES: Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)Cc1ccc(Cl)cc1

InChI Key: InChIKey=NNQOASHONWQOJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016645 (5-[5-Chloro-2-(4-chloro-phenylmethanesulfonyl)-phe...) Show SMILES Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2O4S/c17-10-3-1-9(2-4-10)8-25(23,24)13-6-5-11(18)7-12(13)14-15(21)20-16(22)19-14/h1-7,21H,8H2,(H2,19,20,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair