BDBM50016646 5-[5-Chloro-2-(pentane-1-sulfonyl)-phenyl]-imidazolidine-2,4-dione::CHEMBL19427

SMILES: CCCCCS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O

InChI Key: InChIKey=YWLYJOINDJSMJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016646 (5-[5-Chloro-2-(pentane-1-sulfonyl)-phenyl]-imidazo...) Show SMILES CCCCCS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O Show InChI InChI=1S/C14H17ClN2O4S/c1-2-3-4-7-22(20,21)11-6-5-9(15)8-10(11)12-13(18)17-14(19)16-12/h5-6,8,18H,2-4,7H2,1H3,(H2,16,17,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair