BDBM50016647 4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-propyl-benzenesulfonamide::CHEMBL429059

SMILES: CCCNS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O

InChI Key: InChIKey=NQVFBDVJATWWRY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016647 (4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-propyl-...) Show SMILES CCCNS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O Show InChI InChI=1S/C12H14ClN3O4S/c1-2-5-14-21(19,20)9-4-3-7(13)6-8(9)10-11(17)16-12(18)15-10/h3-4,6,14,17H,2,5H2,1H3,(H2,15,16,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair