BDBM50016649 5-(5-Chloro-2-methylsulfanyl-phenyl)-imidazolidine-2,4-dione::CHEMBL278584

SMILES: CSc1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O

InChI Key: InChIKey=PPLUUCZSOCAHOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016649 (5-(5-Chloro-2-methylsulfanyl-phenyl)-imidazolidine...) Show SMILES CSc1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O Show InChI InChI=1S/C10H9ClN2O2S/c1-16-7-3-2-5(11)4-6(7)8-9(14)13-10(15)12-8/h2-4,14H,1H3,(H2,12,13,15)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair