BDBM50016653 CHEMBL19187::N-Benzyl-4-chloro-2-(2,5-dioxo-imidazolidin-4-yl)-benzenesulfonamide

SMILES: Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCc1ccccc1

InChI Key: InChIKey=FVLYWQFXTTZMGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016653 (CHEMBL19187 | N-Benzyl-4-chloro-2-(2,5-dioxo-imida...) Show SMILES Oc1[nH]c(=O)[nH]c1-c1cc(Cl)ccc1S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C16H14ClN3O4S/c17-11-6-7-13(12(8-11)14-15(21)20-16(22)19-14)25(23,24)18-9-10-4-2-1-3-5-10/h1-8,18,21H,9H2,(H2,19,20,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair