BDBM50016654 CHEMBL19064::N-Butyl-4-chloro-2-(2,5-dioxo-imidazolidin-4-yl)-benzenesulfonamide

SMILES: CCCCNS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O

InChI Key: InChIKey=MBACDSZRAROZOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50016654 (CHEMBL19064 | N-Butyl-4-chloro-2-(2,5-dioxo-imidaz...) Show SMILES CCCCNS(=O)(=O)c1ccc(Cl)cc1-c1[nH]c(=O)[nH]c1O Show InChI InChI=1S/C13H16ClN3O4S/c1-2-3-6-15-22(20,21)10-5-4-8(14)7-9(10)11-12(18)17-13(19)16-11/h4-5,7,15,18H,2-3,6H2,1H3,(H2,16,17,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate				J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G
					More data for this Ligand-Target Pair