BDBM50016661 2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-2-methyl-propyl]-benzoylamino}-pentanedioic acid::CHEMBL23872

SMILES: CC(Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O)Cc1cnc2nc(N)[nH]c(=O)c2n1

InChI Key: InChIKey=WVWNHESCQDVDTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycinamide ribonucleotide formyltransferase (GARFTase) (Homo sapiens (Human))	BDBM50016661 (2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-...) Show SMILES CC(Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O)Cc1cnc2nc(N)[nH]c(=O)c2n1 Show InChI InChI=1S/C22H24N6O6/c1-11(9-14-10-24-18-17(25-14)20(32)28-22(23)27-18)8-12-2-4-13(5-3-12)19(31)26-15(21(33)34)6-7-16(29)30/h2-5,10-11,15H,6-9H2,1H3,(H,26,31)(H,29,30)(H,33,34)(H3,23,24,27,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Alabama Curated by ChEMBL					Assay Description Inhibition of the GAR formyl transferase in lactobacillus casei				J Med Chem 32: 1277-83 (1989) BindingDB Entry DOI: 10.7270/Q20K27J9
					More data for this Ligand-Target Pair