BindingDB PrimarySearch

BDBM50016695 (2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic acid::(S)-2-((S)-2-Amino-propionylamino)-propionic acid::Ala-Ala::CHEMBL17697

SMILES: C[C@H](N)C(=O)N[C@@H](C)C(O)=O

InChI Key: InChIKey=DEFJQIDDEAULHB-IMJSIDKUSA-N

Data: 4 KI 3 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50016695
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 15 member 2 (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Georgia Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing HeLa cells				Biochim Biophys Acta 1240: 1-4 (1996) BindingDB Entry DOI: 10.7270/Q2QN67V2
Medical College of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 15 member 2 (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity to human PepT2 in SKTP cells				Bioorg Med Chem 19: 4544-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Georgia Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing HeLa cells				Biochim Biophys Acta 1240: 1-4 (1996) BindingDB Entry DOI: 10.7270/Q2QN67V2
Medical College of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells				J Med Chem 48: 4410-9 (2005) Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116
					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells				Pharm Res 13: 1631-4 (1996) Article DOI: 10.1023/a:1016476220296 BindingDB Entry DOI: 10.7270/Q2TM7DZF
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells				J Med Chem 49: 3636-44 (2006) Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R
Pharmaceutical Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Activation of human PEPT1 expressed in MDCK cells				J Med Chem 49: 3636-44 (2006) Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R
Pharmaceutical Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50016695 ((2S)-2-{[(2S)-2-aminopropanoyl]amino}propanoic aci...) Show SMILES C[C@H](N)C(=O)N[C@@H](C)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Biological activity was measured against Angiotensin I converting enzyme				J Med Chem 38: 2705-13 (1995) BindingDB Entry DOI: 10.7270/Q2GX4CSN
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair